| 产品详情 |
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| Product Name | MAZ51 |
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| Description | A selective antagonist of the activation of VEGFR-3 by VEGF-C (IC50 = 1 µM); does not inhibit ligand-induced autophosphorylation of VEGFR-2, EGFR, IGF-1R, or PDGFRβ; reduces proliferation and induces apoptosis in a variety of cancer cells in vitro and suppresses tumor growth in vivo |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | biochemical cancer angiogenesis receptor antagonist apoptosis signal transduction protein kinase VEGFR-3 FLT-4 VEGFR3 FLT4 VEGF MAZ-51 signaling VEGF-R3 isoform VEGF-C VEGFC VEGF-D VEGFD lymphatic endothelial cell lymphangiogenesis indoline antagonizes activation VEGFR-2 VEGFR2 autocrine loop induced expression ligand VEGF-A VEGFA reduce proliferation in vitro suppress tumor growth in vivo function survival |
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| Gene, Accession, CAS # | CAS: 163655-37-6 |
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| Catalog # | 16168-5 |
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| Price | |
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| Order / More Info | MAZ51 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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