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| Product Name | Tafluprost |
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| Description | A number of 17-phenyl trinor PGF2α derivatives have been approved for the treatment of glaucoma.{8941,8322,8839,9311} Of these, the ones wherein the 13,14-double bond has been hydrogenated retain relatively good potency, but show a significantly reduced incidence of local irritant side effects.{9736} Alternatively, it was recently reported that analogs incorporating a 15-deoxy-15,15-difluoro modification also had a favorable ophthalmic activity profile.{11598} Tafluprost is a 2-series, 16-phenoxy analog of PGF2α with the 15,15-difluoro substitution. Tafluprost free acid is a very potent FP receptor agonist, with a Ki value of 0.4 nM.{11598} The ester prodrug forms of tafluprost are also potent ocular hypotensives in monkeys. |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | AFP-168 |
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| Gene, Accession, CAS # | CAS: 209860-87-7 |
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| Catalog # | 10005440-1 |
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| Order / More Info | Tafluprost from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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