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| Product Name | Kobe 0065 |
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| Description | An orally active Ras inhibitor with selectivity for H-Ras (Ki = 46 µM); inhibits both anchorage-dependent and -independent growth and induces apoptosis of H-RasG12V-transformed NIH 3T3 cells (IC50 = ~1.5 µM); exhibits antitumor activity in mice bearing a xenograft of human colon cancer SW480 cells expressing K-RasG12V at an oral dose of 80 mg/kg |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Kobe0065 Ras inhibitor H-Ras apoptosis antitumor cancer biochemical intracellular signaling signal transduction |
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| Gene, Accession, CAS # | CAS: 436133-68-5 |
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| Catalog # | 16261-1 |
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| Order / More Info | Kobe 0065 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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