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Product Name | 18-hydroxy-11-deoxy Corticosterone |
Description | A mineralocorticoid secreted by the zona fasciculata of the adrenal gland; biosynthesis is regulated by ACTH as well as angiotensin II, which increases 18-OH-DOC production in isolated human adrenal glomerulosa cells; an intermediate in the metabolism of progesterone; can be formed via conversion of DOC in human SK-MEL188 melanoma cells; can be converted to aldosterone by the capsular portion of rat adrenal glands; increases systolic blood pressure in uninephrectomized saline-drinking rats at 200 µg/rat per day; plasma levels of 18-OH-DOC are elevated in a db/db mouse model of type 2 diabetes |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 18-Hydroxydeoxycorticosterone|18-OH-DOC |
Gene, Accession, CAS # | CAS: 379-68-0 |
Catalog # | 10007851-1 |
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Order / More Info | 18-hydroxy-11-deoxy Corticosterone from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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