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| Product Name | Alogliptin (benzoate salt) |
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| Description | An orally bioavailable DPP-4 inhibitor (IC50 = 6.9 nM) that is selective for DPP-4 over DPP-2, DPP-8, DPP-9, prolyl endopeptidase, FAP, and tryptase (IC50s = >100,000 nM); inhibits DPP-4 activity in vivo in rats, dogs, and cynomolgus monkeys (EC50s = 3.4, 4.9, and 5.6 ng/ml, respectively, in plasma); increases plasma GLP-1 and insulin levels and decreases blood glucose levels during an oral glucose challenge in Zucker fa/fa rats (10 mg/kg); decreases plasma DPP-4 activity and increases GLP-1 levels in diabetic ob/ob mice when administered for 29 days (2.8 mg/kg per day) |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | SYR-322 |
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| Gene, Accession, CAS # | CAS: 850649-62-6 |
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| Catalog # | 23768-50 |
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| Order / More Info | Alogliptin (benzoate salt) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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