| 产品详情 |
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| Antigenic Specificity | RAP1GAP |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 µl, 200 µl |
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| Concentration | > 1 mg/ml |
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| Applications | WB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | RAP1GAP Antibody is a Rabbit Polyclonal antibody against RAP1GAP. This gene encodes a type of GTPase-activating-protein (GAP) that down-regulates the activity of the ras-related RAP1 protein. RAP1 acts as a molecular switch by cycling between an inactive GDP-bound form and an active GTP-bound form. The product of this gene, RAP1GAP, promotes the hydrolysis of bound GTP and hence returns RAP1 to the inactive state whereas other proteins, guanine nucleotide exchange factors (GEFs), act as RAP1 activators by facilitating the conversion of RAP1 from the GDP- to the GTP-bound form. In general, ras subfamily proteins, such as RAP1, play key roles in receptor-linked signaling pathways that control cell growth and differentiation. RAP1 plays a role in diverse processes such as cell proliferation, adhesion, differentiation, and embryogenesis. Alternative splicing results in multiple transcript variants encoding distinct proteins. |
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| Immunogen | Recombinant protein of human RAP1GAP. |
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| Other Names | KIAA0474; RAP1 GTPase activating protein; Rap1 GTPase-activating protein 1; RAP1; GTPase activating protein 1; RAP1GA1; RAP1GAP; Rap1GAP1; RAP1GAPII; RAPGAP; RPGP1 |
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| Gene, Accession # | RAP1GAP, Gene ID: 5909, SwissProt: P47736 |
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| Catalog # | abx002991 |
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| Price | |
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| Order / More Info | RAP1GAP Antibody from ABBEXA |
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| Product Specific References | n/a |
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