| 产品详情 |
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| Product Name | all-trans Retinoic Acid |
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| Description | A vitamin A metabolite and RAR ligand (IC50s = 9, 3, and 10 nM for RARα, RARβ, and RARγ, respectively); induces expression of a luciferase reporter in COS-7 cells expressing RARα, RARβ, or RARγ (EC50s = 169, 9, and 2 nM, respectively); reduces TPA-induced papilloma formation in mice at 17 nmol; reduces bile duct proliferation, hydroxyproline levels, and liver inflammation in a rat model of α-naphthylisothiocyanate-induced chronic cholestasis; reduces plasma levels of alkaline phosphatase and bile salts in the Mdr2-/- mouse model of cholestasis; reduces hepatic fat accumulation, triglycerides, body weight, and serum glucose levels in mice with Western diet-induced obesity, |
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| Size | 1 g |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | atRA|NSC 122578|NSC 122758|RA|Vitamin A Acid |
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| Gene, Accession, CAS # | CAS: 302-79-4 |
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| Catalog # | 11017-1 |
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| Order / More Info | all-trans Retinoic Acid from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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