产品详情 |
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Antigenic Specificity | BRD4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunohistochemistry: 1:100-1:500 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | BRD4 Polyclonal Antibody. BRD4, a ubiquitously expressed nuclear phosphoprotein, is a member of BET protein family. It is a human homolog of mouse MCAP and consists of 2 N-terminal bromodomains, a central ET-domain, and several kinase-like motifs in its N-terminus. It is expressed as 2 isoforms; the longer variant has a C-terminus region with a praline and glutamine-rich domains.BRD4 is a chromatin-binding protein whose expression is induced in response to growth stimuli. BRD4 acts at different stages of the cell cycle by interacting with proteins including RFC and SPA-1 and regulates cell growth. It also has a role in regulating chromosomal dynamics during mitosis. BRD4 functions as a cellular target for E2 protein of papillomavirus. |
Immunogen | n/a |
Other Names | HUNK1 |
Gene, Accession # | Entrez: 23476, 57261; Uniprot: O60885, Q9ESU6 |
Catalog # | IHC-00396 |
Price | |
Order / More Info | BRD4 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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