产品详情 |
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Antigenic Specificity | BRD4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | bovine, canine, equine, guinea pig, human, mouse, rabbit, rat |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | ChIP assay: 0.5 µg, Immunocytochemistry: 4 µg/mL, Immunofluorescence: 4 µg/mL, Western Blot: 0.2-1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | BRD4 Polyclonal Antibody. BRD4, a ubiquitously expressed nuclear phosphoprotein, is a member of BET protein family. It is a human homolog of mouse MCAP and consists of 2 N-terminal bromodomains, a central ET-domain, and several kinase-like motifs in its N-terminus. It is expressed as 2 isoforms; longer variant has a C-terminus region with a praline and glutamine-rich domains. BRD4 is a chromatin-binding protein whose expression is induced in response to growth stimuli. BRD4 acts at different stages of cell cycle by interacting with proteins including RFC and SPA-1 and regulates cell growth. It also has a role in regulating chromosomal dynamics during mitosis. BRD4 functions as a cellular target for E2 protein of papillomavirus. |
Immunogen | n/a |
Other Names | Bromodomain containing 4, CAP, HUNKI, MCAP, HUNK1 |
Gene, Accession # | Entrez: 100062072, 100352214, 100717142, 23476, 362844, 484869, 57261, 614048; Uniprot: O60885, Q9ESU6 |
Catalog # | PA5-41550 |
Price | |
Order / More Info | BRD4 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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