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| Antigenic Specificity | BRD4 |
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| Clone | 23476 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunoprecipitation: 2 µg |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | BRD4 Monoclonal Antibody (23476). BRD4, a ubiquitously expressed nuclear phosphoprotein, is a member of BET protein family. It is a human homolog of mouse MCAP and consists of 2 N-terminal bromodomains, a central ET-domain, and several kinase-like motifs in its N-terminus. It is expressed as 2 isoforms; longer variant has a C-terminus region with a praline and glutamine-rich domains. BRD4 is a chromatin-binding protein whose expression is induced in response to growth stimuli. BRD4 acts at different stages of cell cycle by interacting with proteins including RFC and SPA-1 and regulates cell growth. It also has a role in regulating chromosomal dynamics during mitosis. BRD4 functions as a cellular target for E2 protein of papillomavirus. |
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| Immunogen | n/a |
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| Other Names | BRD4-NUT fusion oncoprotein, BRD4-NUT FUSION |
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| Gene, Accession # | Entrez: 23476; Uniprot: O60885 |
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| Catalog # | 730007 |
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| Price | |
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| Order / More Info | BRD4 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 25452129, 26121405 |
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