| 产品详情 |
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| Antigenic Specificity | CK2 alpha-2 |
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| Clone | 1E1 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1:200 - 1:400, Western Blot: 1:500 - 1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CK2 alpha-2 Monoclonal Antibody (1E1). Casein kinase II (CK2) is a constitutively active, ubiquitously expressed serine/threonine protein kinase that is thought to have a regulatory function in cell proliferation, cell differentiation and apoptosis. CK2 functions as a tetrameric complex consisting of two regulatory beta-subunits and two catalytic units (alpha and alpha') in a homomeric or heteromeric conformation. Whilst the alpha- and alpha'-subunits are catalytically identical, proteins that regulate CK2, such as cdc2 and Hsp90, preferentially bind to the alpha and not the alpha'-subunit. CK2 can phosphorylate a number of key intracellular signaling proteins implicated in tumor suppression (p53 and PTEN) and tumorigenesis (myc, jun, NF-ka |
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| Immunogen | n/a |
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| Other Names | n/a |
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| Gene, Accession # | Entrez: 13000, 1459, 307641; Uniprot: O54833, P19784 |
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| Catalog # | MA5-17062 |
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| Price | |
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| Order / More Info | CK2 alpha-2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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