| 产品详情 |
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| Product Name | Cinobufagin |
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| Description | A cardiotonic steroid that has diverse biological activities; inhibits Na+/K+-ATPase activity in guinea pig heart ventricular muscle homogenates at 0.3 µM; is cytotoxic to HCT116 cells in vitro (IC50s = <50 ng/ml at 48- and 72-hour time points) and induces apoptosis; reduces tumor growth in an HCT116 mouse xenograft model at 10 mg/kg; inhibits LPS-induced expression of MHC class II, CD80, and CD86 and release of IL-6, IL-8, TNF-α, and IL-10 in human monocyte-derived dendritic cells at 1 µg/ml; increases expression of hBD2 and hBD3 in dendritic cells; exhibits antinociceptive effects in mice |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | NSC 90325 |
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| Gene, Accession, CAS # | CAS: 470-37-1 |
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| Catalog # | 19844-25 |
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| Price | |
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| Order / More Info | Cinobufagin from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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