| 产品详情 |
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| Product Name | SNX-2112 |
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| Description | A potent Hsp90 inhibitor (Kd = 30 nM); induces down-regulation of client proteins HER2 and Akt in vitro; inhibits proliferation in a panel of cancer cell lines (IC50s = 10-50 nM); inhibits tumor growth in a BT474 breast cancer mouse xenograft model; active metabolite of the prodrug SNX-5542 and preferentially accumulates in tumor tissue of mice treated with a single oral dose of 75 mg/kg SNX-5542 |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | PF-04928473 |
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| Gene, Accession, CAS # | CAS: 908112-43-6 |
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| Catalog # | 22359-5 |
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| Price | |
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| Order / More Info | SNX-2112 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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