| 产品详情 |
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| Antigenic Specificity | Phospho-CPI-17 (Thr38) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-CPI-17 (Thr38) Polyclonal Antibody. CPI-17 is a phosphorylation-dependent inhibitory protein for smooth muscle myosin phosphate. CPI-17 was originally identified as a PKC-potentiated inhibitory protein of protein phosphatase-1, which is dominantly expressed in smooth muscle. Phosphorylation at Threonine 38, in vitro, by PKC or Rho-kinase enhances the inhibitory potency toward myosin phosphatase. CPI-17 is also phosphorylated at Threonine 38 by protein kinase N and might be involved in the calcium sensitization of smooth muscle contraction as a downstream effector of Rho and/or arachidonic acid. CPI-17 is dually phosphorylated at Serine 12 and Threonine 38 by a MYPT-associated kinase, M110 kinase. |
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| Immunogen | n/a |
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| Other Names | Protein phosphatase 1 regulatory subunit 14A, 17 kDa PKC-potentiated inhibitory protein of PP1, Protein kinase C-potentiated inhibitor protein of 17 kDa, CPI-17, CPI17, PPP1INL, PPP1R14A |
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| Gene, Accession # | Entrez: 114004, 68458, 94274; Uniprot: Q91VC7, Q96A00, Q99MC0 |
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| Catalog # | PA5-36842 |
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| Price | |
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| Order / More Info | Phospho-CPI-17 (Thr38) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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