| 产品详情 |
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| Antigenic Specificity | BAX |
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| Clone | monoclonal |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2b |
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| Format | purified |
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| Size | 80 µl, 400 µl |
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| Concentration | n/a |
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| Applications | WB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero or homodimers and act as anti or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. This BAX antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 28-56 amino acids from human BAX. |
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| Immunogen | Human BAX. |
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| Other Names | Apoptosis regulator BAX; BAX; Bcl-2-like protein 4; BCL2-associated X protein; Bcl2-L-4; BCL2L4; membrane isoform alpha; BAXA; bax protein; cytoplasmic isoform delta; bax; GLUT10 |
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| Gene, Accession # | SwissProt: Q07812 |
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| Catalog # | abx025468 |
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| Price | |
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| Order / More Info | BAX Antibody from ABBEXA |
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| Product Specific References | n/a |
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| 产品资料 |
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