产品详情 |
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Antigenic Specificity | TCR beta |
Clone | H57-597 |
Host Species | Armenian Hamster |
Reactive Species | mouse |
Isotype | IgG |
Format | PerCP-Cyanine5.5 conjugate |
Size | 25 µg |
Concentration | n/a |
Applications | Flow Cytometry: 0.25 µg/test |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TCR beta Monoclonal Antibody (H57-597), PerCP-Cyanine5.5, eBioscience™. The ability of T cell receptors (TCR) to discriminate foreign from self-peptides presented by major histocompatibility complex (MHC) class II molecules is essential for an effective adaptive immune response. TCR recognition of self-peptides has been linked to autoimmune disease. Mutant self-peptides have been associated with tumors. Engagement of TCRs by a family of bacterial toxins know as superantigens has been responsible for toxic shock syndrome. Autoantibodies to V beta segments of T cell receptors have been isolated from patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). The autoantibodies block TH1-mediated inflammatory autodest |
Immunogen | n/a |
Other Names | TCRbeta, Tib |
Gene, Accession # | Entrez: 21577 |
Catalog # | 45-5961-80 |
Price | |
Order / More Info | TCR beta Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 19915059, 20585036, 21419662, 21775286, 21946417, 22043016, 22201126, 22475534, 22676339, 23644504, 23900386, 24048441, 24098366, 24190658, 24312094, 24551105, 24657994, 25264896, 25858227, 25941590, 25956511, 26216893, 26416167, 26505904, 26647186, 26822477, 27045020, 27257599, 27670070, 28008921, 28382040, 28963568, 29136506, 29249358, 29383154 |
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