产品详情 |
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Antigenic Specificity | TCR beta |
Clone | H57-597 |
Host Species | Armenian Hamster |
Reactive Species | mouse |
Isotype | IgG |
Format | PE-Cyanine7 conjugate |
Size | 25 µg |
Concentration | n/a |
Applications | Flow Cytometry: 0.125 µg/test |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TCR beta Monoclonal Antibody (H57-597), PE-Cyanine7, eBioscience™. The ability of T cell receptors (TCR) to discriminate foreign from self-peptides presented by major histocompatibility complex (MHC) class II molecules is essential for an effective adaptive immune response. TCR recognition of self-peptides has been linked to autoimmune disease. Mutant self-peptides have been associated with tumors. Engagement of TCRs by a family of bacterial toxins know as superantigens has been responsible for toxic shock syndrome. Autoantibodies to V beta segments of T cell receptors have been isolated from patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). The autoantibodies block TH1-mediated inflammatory autodestructi |
Immunogen | n/a |
Other Names | TCRbeta, Tib |
Gene, Accession # | Entrez: 21577 |
Catalog # | 25-5961-80 |
Price | |
Order / More Info | TCR beta Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 20303345, 23626013, 23644504, 23943651, 24796279, 25385531, 25956511, 26416167, 26647186, 27045020, 27186978, 27378849, 27670070, 28382040, 28963568, 29136506, 29249358 |
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