产品详情 |
Edit |   |
Antigenic Specificity | TCR beta |
Clone | H57-597 |
Host Species | Armenian Hamster |
Reactive Species | mouse |
Isotype | IgG |
Format | unconjugated, functional grade |
Size | 500 µg |
Concentration | n/a |
Applications | Flow Cytometry: 0.5 µg/test, Functional Assay: Assay-Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TCR beta Monoclonal Antibody (H57-597), Functional Grade, eBioscience™. The ability of T cell receptors (TCR) to discriminate foreign from self-peptides presented by major histocompatibility complex (MHC) class II molecules is essential for an effective adaptive immune response. TCR recognition of self-peptides has been linked to autoimmune disease. Mutant self-peptides have been associated with tumors. Engagement of TCRs by a family of bacterial toxins know as superantigens has been responsible for toxic shock syndrome. Autoantibodies to V beta segments of T cell receptors have been isolated from patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). The autoantibodies block TH1-mediated inflammatory autodest |
Immunogen | n/a |
Other Names | TCRbeta, Tib |
Gene, Accession # | Entrez: 21577 |
Catalog # | 16-5961-85 |
Price | |
Order / More Info | TCR beta Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 22701598, 23644504, 25847946, 25956511, 26416167, 26647186, 27045020, 27670070, 28382040, 28874772, 28963568, 29136506, 29249358 |
产品资料 |
|
|