产品详情 |
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Antigenic Specificity | TCR beta |
Clone | H57-597 |
Host Species | Armenian Hamster |
Reactive Species | mouse |
Isotype | IgG |
Format | fluorescein (FITC) conjugate |
Size | 500 µg |
Concentration | n/a |
Applications | Flow Cytometry: 0.5 µg/test |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TCR beta Monoclonal Antibody (H57-597), FITC, eBioscience™. The ability of T cell receptors (TCR) to discriminate foreign from self-peptides presented by major histocompatibility complex (MHC) class II molecules is essential for an effective adaptive immune response. TCR recognition of self-peptides has been linked to autoimmune disease. Mutant self-peptides have been associated with tumors. Engagement of TCRs by a family of bacterial toxins know as superantigens has been responsible for toxic shock syndrome. Autoantibodies to V beta segments of T cell receptors have been isolated from patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). The autoantibodies block TH1-mediated inflammatory autodestructive reac |
Immunogen | n/a |
Other Names | TCRbeta, Tib |
Gene, Accession # | Entrez: 21577 |
Catalog # | 11-5961-85 |
Price | |
Order / More Info | TCR beta Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 15780989, 17170126, 17897956, 18391003, 18981104, 19056387, 19139167, 19443662, 19644014, 19841086, 20107189, 20303345, 20837519, 21074460, 21135167, 21339326, 21518798, 21912419, 22144492, 22238605, 22331068, 22430207, 22504642, 22960222, 23190605, 23644504, 24018532, 24172908, 24263053, 24436372, 24470501, 24632942, 25070844, 25108421, 25261477, 25385531, 25403443, 25474593, 25724068, 25803615, 25956511, 25987726, 26070118, 26416167, 26647186, 26739627, 27045020, 27150250, 27610573, 27670070, 27824136, 28382040, 28963568, 29116089, 29136506, 29249358, 29361554, 29440650 |
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