| 产品详情 |
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| Antigenic Specificity | Grim-19 |
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| Clone | 1A8 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG2b |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: Assay-Dependent, Immunofluorescence: Assay-Dependent, Immunohistochemistry (Paraffin): Assay-Dependent, Western Blot: 5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Grim-19 Monoclonal Antibody (1A8), eBioscience™. A novel gene associated with Retinoid-IFN-induced Mortality (GRIM) GRIM-19 gene was identified. Antisense expression of GRIM-19 confers a strong resistance against IFN/RA-induced death by reducing the intracellular levels of GRIM-19 protein. Overexpression of GRIM-19 enhances cell death in response to IFN/RA. GRIM-19 is primarily a nuclear protein whose expression is induced by the IFN/RA combination. These data indicate that GRIM-19 is a novel cell death-regulatory molecule. |
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| Immunogen | n/a |
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| Other Names | NADH-ubiquinone oxidoreductase B16.6 subunit, Complex I-B16.6, CI-B16.6, Gene associated with retinoic-interferon-induced mortality 19 protein, Cell d |
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| Gene, Accession # | Entrez: 100911483, 314759, 51079, 67184; Uniprot: Q9ERS2, Q9P0J0 |
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| Catalog # | 14-9937-82 |
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| Price | |
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| Order / More Info | Grim-19 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 22451716, 23414756, 27883012 |
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| 产品资料 |
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