产品详情 |
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Product Name | Kukoamine A |
Description | A spermine alkaloid with diverse biological activities; induces autophagy and increases cell viability in an SH-SY5Y cell model of MPP-induced injury at 20 and 40 µM; increases the number of dopamine neurons in the substantia nigra and striatum, decreases α-synuclein expression, and improves motor function in an MPTP mouse model of Parkinson's disease at 20 mg/kg per day; decreases IL-1β, TNF-α, and COX-2 protein levels in the hippocampus and increases hippocampal neurogenesis in a rat model of radiation injury at 10 and 20 mg/kg; selectively inhibits trypanothione reductase (Ki = 1.8 µM) over human glutathione reductase (Ki = >10 mM) |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Lycium anti-cancer antiinflammatory U 251 WJ 1 SHSY5Y MP TP IL1β TNFα COX2 |
Gene, Accession, CAS # | CAS: 75288-96-9 |
Catalog # | 25139-1 |
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Order / More Info | Kukoamine A from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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