产品详情 |
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Product Name | YYA-021 |
Description | A small molecule CD4 mimetic; inhibits gp120 and CD4 interaction, preventing HIV from entering cells; inhibits infection of PM1/CCR5 cells from lab isolates of the HIV-1 strains IIIB (X4, Sub B) and 89.6 (dual, Sub B) (IC50s = 23 and 41 µM, respectively); inhibits infection of PM1/CCR5 cells from clinical isolates of the fTOI (R5, Sub B) and KYAG strains (R5, Sub B) (IC50s = 16 and 51 µM, respectively); inhibits HIV-1 infection of TZM-bl cells (IC50 = 8.4 µM); reduces viability of mock-infected PM1/CCR5 cells with cytotoxic concentration (CC50) values of 260 µM |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | YYA021 CD-4 Human Immunodeficiency Virus envelope glycoprotein YYA21 |
Gene, Accession, CAS # | CAS: 144217-65-2 |
Catalog # | 22915-5 |
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Order / More Info | YYA-021 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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