| 产品详情 |
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| Antigenic Specificity | DARC |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 2.5 µg/mL, Western Blot: 0.5-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | DARC Polyclonal Antibody. DARC, also known as the Duffy antigen/chemokine receptor, is a seven-transmembrane protein homologous to the classical chemokine G-protein coupled receptors (GPCRs) with the exception of the motif required for G protein coupling. DARC can bind with high affinity several chemokines without transducing any signal, suggesting it may modulate the signals normally induced by these chemokines. Recently, DARC was found to interact with KAI1, a four transmembrane protein recently identified as a tumor metastasis suppressor protein. It is thought that tumor cells dislodged from the primary tumor and expressing KAI1 interact with DARC proteins expressed on vascular cells, transmitting a senescent signal to the tumor cells, w |
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| Immunogen | n/a |
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| Other Names | CTA-134P22.3, CCBP1, CD234, Dfy, FY, GPD, GpFy, WBCQ1; Duffy antigen/chemokine receptor; Duffy blood group antigen; Fy glycoprotein; glycoprotein D; plasmodium vivax receptor |
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| Gene, Accession # | Entrez: 13349, 2532, 689105; Uniprot: Q16570, Q9QUI6 |
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| Catalog # | PA5-20357 |
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| Price | |
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| Order / More Info | DARC Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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