| 产品详情 |
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| Antigenic Specificity | ACK1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:500-1:3000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ACK1 Polyclonal Antibody. This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. |
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| Immunogen | n/a |
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| Other Names | ACK, ACK-1, ACK1, p21cdc42Hs, activated CDC42 kinase 1, activated Cdc42-associated kinase 1, activated p21cdc42Hs kinase, tyrosine kinase non-receptor protein 2 |
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| Gene, Accession # | Entrez: 10188, 51789; Uniprot: O54967, Q07912 |
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| Catalog # | PA5-28389 |
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| Price | |
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| Order / More Info | ACK1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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