| 产品详情 |
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| Antigenic Specificity | ACK1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 80 µl, 400 µl |
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| Concentration | n/a |
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| Applications | WB, IHC. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ACK1 is a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP) stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. This ACK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 934-964 amino acids from the C-terminal region of human ACK1. |
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| Immunogen | Human ACK1. |
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| Other Names | TNK2; ACK1; Activated CDC42 kinase 1; Tyrosine kinase non-receptor protein 2 |
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| Gene, Accession # | Accession: NP_001010938.1, NP_005772.3, SwissProt: Q07912 |
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| Catalog # | abx033628 |
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| Price | |
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| Order / More Info | ACK1 Antibody from ABBEXA |
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| Product Specific References | n/a |
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