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| Antigenic Specificity | TCF3 |
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| Clone | monoclonal |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | ascites |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | ELISA, WB, FCM. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | E2A is a transcription factor that plays major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Heterodimers between E2A and tissue-specific basic helix-loop-helix (bHLH) Dimers bind DNA on E-box motifs: 5'- CANNTG-3'. Binds to the kappa -E2 site in the kappa immunoglobulin gene enhancer. Deletions in E2A have been observed in a subset of pre-B-cell acute lymphoblastic leukemia (B-ALL) cases. Two alternatively spliced human isoforms have been described. |
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| Immunogen | Purified recombinant fragment of human TCF3 expressed in E. Coli. |
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| Other Names | E12; Immunoglobulin enhancer binding factor E12/E47; Immunoglobulin transcription factor-1; ITF1; Kappa-E2-binding factor; TCF-3; TCF3; TFE2; transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47); Transcription factor E2-alpha; Transcription factor ITF-1; Transcription factor-3; E2A; E47; VDIR; bHLHb21; transcription factor 3; NOL1-TCF3 fusion; VDR interacting repressor; class B basic helix-loop-helix protein 21; helix-loop-helix protein HE47; immunoglobulin transcription factor 1; nega; MGC129647; MGC129648; Immunoglobulin enhancer-binding factor E12/E47; Immunoglobulin tra |
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| Gene, Accession # | TCF3, Gene ID: 6929, SwissProt: P15923 |
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| Catalog # | abx010676 |
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| Price | |
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| Order / More Info | TCF3 Antibody from ABBEXA |
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| Product Specific References | n/a |
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