| 产品详情 |
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| Antigenic Specificity | TCF3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 µl, 200 µl |
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| Concentration | > 1 mg/ml |
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| Applications | WB, IHC, FCM. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TCF3 Antibody is a Rabbit Polyclonal antibody against TCF3. This gene encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1;19), with PBX1), childhood leukemia (t(19;19), with TFPT) and acute leukemia (t(12;19), with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. |
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| Immunogen | Recombinant protein of human TCF3. |
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| Other Names | E12; Immunoglobulin enhancer binding factor E12/E47; Immunoglobulin transcription factor-1; ITF1; Kappa-E2-binding factor; TCF-3; TCF3; TFE2; transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47); Transcription factor E2-alpha; Transcription factor ITF-1; Transcription factor-3; E2A; E47; VDIR; bHLHb21; transcription factor 3; NOL1-TCF3 fusion; VDR interacting repressor; class B basic helix-loop-helix protein 21; helix-loop-helix protein HE47; immunoglobulin transcription factor 1; nega; MGC129647; MGC129648; Immunoglobulin enhancer-binding factor E12/E47; Immunoglobulin tra |
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| Gene, Accession # | TCF3, Gene ID: 6929, SwissProt: P15923 |
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| Catalog # | abx000739 |
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| Price | |
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| Order / More Info | TCF3 Antibody from ABBEXA |
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| Product Specific References | n/a |
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