| 产品详情 |
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| Antigenic Specificity | PICK1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1.7 µg/mL, Immunofluorescence: 1-2 µg/mL, Immunoprecipitation: Assay dependent, Western Blot: 2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PICK1 Polyclonal Antibody. PSD-95/DLG/ZO-1 (PDZ) domain-containing proteins play a central role in synaptic membrane protein localization. The protein interacting with protein kinase C (PICK1) is a synaptic PDZ domain protein that also contains a coiled-coil and acidic domain. Studies indicate that PICK1 functions as a targeting and transport protein and has been shown to interact with protein kinase C alpha (PKCalpha), AMPA-type glutamate receptors, and several other membrane receptors via its PDZ domain. The interaction of PICK1 with PKCalpha is highly dependent on the activation of the kinase. It appears that PICK1 directs the activated form of PKCalpha to membrane anchored GluR2. Once phosphorylated by PKCalpha, GluR2 is released from t |
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| Immunogen | n/a |
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| Other Names | Protein Interacting with Protein Kinase C, PRKCA-binding protein, Protein kinase C-alpha-binding protein, Protein interacting with C kinase 1 |
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| Gene, Accession # | Entrez: 18693, 84591; Uniprot: Q62083, Q9EP80 |
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| Catalog # | PA1-073 |
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| Price | |
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| Order / More Info | PICK1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 14672991, 21106840, 25784538, 26472923, 9405395 |
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