产品详情 |
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Antigenic Specificity | NEK7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 20 µL |
Concentration | n/a |
Applications | Immunohistochemistry: 1:200-1:800, Western Blot: 1:1,000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NEK7 Polyclonal Antibody. NEK9, a NEK type protein kinase, regulates chromosome alignment and segregation in mitosis. The protein has a N-terminal NIMA-like catalytic domain, a central domain with homology to the guanine nucleotide exchange factor for the GTPase Ran (RCC1), and a C-terminal coiled-coil domain. It is phosphorylated by active p34(Cdc2) and is capable of autophosphorylation and oligomerization. The activated protein binds Nek6 and RCC1, and has been shown to associate with the human homolog of the Drosophila protein Bicaudal D (Bicd2) in vivo and to phosphorylate this coiled-coil protein in vitro. NEK9 expression has been documented in normal human brain. ESTs have been isolated from several tissue libraries, including normal |
Immunogen | n/a |
Other Names | Never In Mitosis Gene A-Related Kinase 9 |
Gene, Accession # | Entrez: 140609; Uniprot: Q8TDX7 |
Catalog # | A302-684A-T |
Price | |
Order / More Info | NEK7 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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