产品详情 |
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Antigenic Specificity | PREB |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunohistochemistry: 1:20-1:50, Western Blot: 0.4 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PREB Polyclonal Antibody. Prolactin (PRL) expression in the pituitary is limited to specific cells. Pit-1 is a pituitary specific transcription factor that plays an important role in PRL expression, both in mature organism and during development. The PRL promoter contains numerous Pit-1 binding sites and these sites have been implicated in both basal level and kinase-mediated gene expression. The most proximal of these binding sites, termed 1P, has been shown to direct a response to numerous signals, such as cAMP and various G-proteins. A novel protein, termed PREB (prolactin regulatory element binding protein), has been recently identified that regulates PRL gene expression through the 1P site, though it contains no discernable DNA-binding |
Immunogen | n/a |
Other Names | Prolactin Regulatory Element Binding Protein |
Gene, Accession # | Entrez: 10113, 50907, 58842; Uniprot: Q9HCU5, Q9WTV0, Q9WUQ2 |
Catalog # | PA5-53066 |
Price | |
Order / More Info | PREB Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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