| 产品详情 |
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| Antigenic Specificity | JAK3 |
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| Clone | 7HCLC |
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| Host Species | Recombinant Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 2 µg/mL, Immunofluorescence: 2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | JAK3 Antibody (7HCLC), ABfinity™ Rabbit Oligoclonal. Janus Activating Kinase (JAK) is a number of related tyrosine kinases involved in cytoplasmic signal transduction. In response to a varitety of cytokine or related factors (e.g., interferon, interleukins), JAKs are activated via phosphorylation at 2 adjacent tyrosine residues. The activation of JAKs can lead to the phosphorylation of STAT (signal transducers and activatiors of transcription) proteins, which dimerize and translocate to the nucleus. Once translocated to the nucleus, the STAT proteins can modify transcription of numerous genes, including interferon-stimulated genes. JAK2 is required for the IFN gamma-receptor complex initiation and JAK1 functions as an amplifier. Howev |
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| Immunogen | n/a |
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| Other Names | L-JAK |
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| Gene, Accession # | Entrez: 3718; Uniprot: P52333 |
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| Catalog # | 711602 |
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| Price | |
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| Order / More Info | JAK3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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