| 产品详情 |
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| Antigenic Specificity | JAK2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blot: Assay Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | JAK2 Polyclonal Antibody. Janus Activating Kinase 2 (JAK2) is a non-rececptor tyrosine kinase involved in various processes such as cell growth, development, differentiation, and histone modifications. In response to a varitety of cytokine or related factors (e.g., interferon, interleukins), JAKs are activated via phosphorylation at 2 adjacent tyrosine residues. The activation of JAKs can lead to the phosphorylation of STAT (signal transducers and activatiors of transcription) proteins, which dimerize and translocate to the nucleus. Once translocated to the nucleus, the STAT proteins can modify transcription of numerous genes, including interferon-stimulated genes. JAK2 is required for the IFN gamma-receptor complex initiation and JAK1 func |
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| Immunogen | n/a |
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| Other Names | EC 2.7.10.2, JAK-2, JAK2, Janus kinase 2, kinase Jak2 |
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| Gene, Accession # | Entrez: 16452, 3717; Uniprot: O60674, Q62120 |
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| Catalog # | 44-406G |
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| Price | |
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| Order / More Info | JAK2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 12093796, 12354677, 15917293, 17551829 |
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