| 产品详情 |
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| Antigenic Specificity | Vinculin |
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| Clone | SP117 |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | purified |
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| Size | 500 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:100 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Vinculin Monoclonal Antibody (SP117). Vinculin (VCL) is a cytoskeletal protein associated with cell-cell and cell-extracellular matrix adherens-type junctions. It functions as one of several interacting proteins involved in anchoring F-actin to the membrane. It has been shown that a sequence of molecular interactions might be involved in the transmembrane assembly of adhesion plaques. In the assembly of adhesion plaques, the beta subunit of integrin binds to talin. Talin binds to vinculin that interacts with alpha-actinin and possibly with itself. Since alpha-actinin binds to and cross-links actin filaments, vinculin represents a key element in the transmembrane linkage of the extracellular matrix to the cytoplasmic microfilament system. Mu |
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| Immunogen | n/a |
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| Other Names | CMD1W, CMH15, MVCL, metavinculin |
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| Gene, Accession # | Entrez: 7414; Uniprot: P18206 |
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| Catalog # | MA5-16424 |
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| Price | |
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| Order / More Info | Vinculin Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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