产品详情 |
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Antigenic Specificity | VE-cadherin |
Clone | 3D5C7 |
Host Species | Mouse |
Reactive Species | human, rat |
Isotype | IgG1 |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Flow Cytometry: 1:200 - 1:400, Western Blot: 1:500 - 1:2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | VE-cadherin Monoclonal Antibody (3D5C7). This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been |
Immunogen | n/a |
Other Names | Cadherin-5, Vascular endothelial cadherin, VE-cadherin, 7B4 antigen, CD144 antigen, CDH5 |
Gene, Accession # | Entrez: 1003, 307618; Uniprot: P33151 |
Catalog # | MA5-17050 |
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Order / More Info | VE-cadherin Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 27020249 |
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