产品详情 |
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Antigenic Specificity | VDR |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | chicken, human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Gel Shift: Assay dependent, Immunoprecipitation: Assay dependent, Western Blot: 1:100 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | VDR Polyclonal Antibody. Steroid receptors are ligand-dependent intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate hormone. The 1,25-dihydroxy-vitamin D3 receptor (VDR) belongs to the superfamily of steroid hormone receptors which includes estrogen, progesterone, glucocorticoid, androgen, and thyroid hormone receptors. Vitamin D modulates calcium and phosphorus homeostasis, bone remodeling, cell growth regulation, and differentiation. Studies have found VDR in the intestine, bone, kidney, epidermis, and cells of the endocrine immune system. Repression of T-cell proliferation and interleukin-2 (IL-2) gene expresion, for example, occurs when VDR bi |
Immunogen | n/a |
Other Names | VDR, 125 dihydroxyvitamin D3 receptor, NR1I1, Vitamin D3 receptor |
Gene, Accession # | Entrez: 22337, 24873, 395988, 7421; Uniprot: O42392, P11473, P13053, P48281 |
Catalog # | PA1-711 |
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Order / More Info | VDR Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 10827014, 15709781, 22588001 |
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