产品详情 |
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Antigenic Specificity | ING4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot: Assay Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ING4 Polyclonal Antibody. The ING4 gene belongs to the ING (Inhibitor of Growth) family of tumor suppressors. All five members of the ING protein family identified to date contain a highly conserved plant homeodomain (PHD) finger motif at the C-terminal end, which is found in transcription factors that modulate chromatin structure. ING proteins have been shown to form transcriptional complexes leading to activation of responsive genes that mediate a wide range of cellular functions, including growth arrest, DNA repair, gene transcription, apoptosis, and senescence. The candidate tumor suppressor ING4 has a role in brain tumor pathogenesis, and is involved in regulating tumor growth and angiogenesis. Expression of ING4 is reduced in gliomas |
Immunogen | n/a |
Other Names | Inhibitor of growth protein 4, p29ING4, ING4, My036 |
Gene, Accession # | Entrez: 28019, 51147; Uniprot: Q8C0D7, Q9UNL4 |
Catalog # | 40-7700 |
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Order / More Info | ING4 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 20716169, 25790869, 28781682, 29163768 |
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