| 产品详情 |
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| Antigenic Specificity | ING3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | bovine, canine, equine, guinea pig, human, mouse, rabbit, rat, zebrafish |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 5 µg/mL, Western Blot: 0.2-1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ING3 Polyclonal Antibody. The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed. |
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| Immunogen | n/a |
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| Other Names | Inhibitor of growth family member 3, Eaf4, FLJ20089, ING2, p47ING3, MEAF4 |
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| Gene, Accession # | Entrez: 100056220, 100354601, 100721269, 312154, 393911, 475299, 513000, 54556, 71777; Uniprot: Q498T3, Q8VEK6, Q9NXR8 |
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| Catalog # | PA5-40702 |
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| Price | |
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| Order / More Info | ING3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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