产品详情 |
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Antigenic Specificity | Complement C5a |
Clone | 561 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | ELISA: 1:50, Functional Assay: 1:50, Immunoprecipitation: 1:50, Western Blot: 1:50 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Complement C5a Monoclonal Antibody (561). This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals m |
Immunogen | n/a |
Other Names | DADB-112B14.11, C4B1, C4B12, C4B2, C4B3, C4B5, C4F, CH, CO4, CPAMD3, FLJ60561, MGC164979 |
Gene, Accession # | Entrez: 727; Uniprot: P01031 |
Catalog # | MA1-40159 |
Price | |
Order / More Info | Complement C5a Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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