产品详情 |
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Product Name | APY-29 |
Description | A modulator of IRE1α function; binds to the ATP-binding site on IRE1α, where it inhibits autophosphorylation (IC50 = 280 nM) and enhances its RNase function (EC50 = 460 nM); restores the ability of dephosphoylated IRE1α to cleave XBP1 mRNA in a dose-dependent manner; enhances IRE1α oligomerization in a crosslinking assay, |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | APY29 IRE1a IRE-1a XBP-1 ribonuclease |
Gene, Accession, CAS # | CAS: 1216665-49-4 |
Catalog # | 22913-10 |
Price | |
Order / More Info | APY-29 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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