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| Antigenic Specificity | NMDAR2B |
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| Clone | B3-13B11 |
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| Host Species | Mouse |
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| Reactive Species | canine, human, nonhuman primate, rat |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | ELISA: 1.0-5 µg/mL, Immunohistochemistry (Frozen): 5-10 µg/mL, Western Blot: 1-5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | NMDAR2B Monoclonal Antibody (B3-13B11). NMDAR2B is a member of the N-methyl-D-aspartate (NMDA) class of ionotropic glutamate receptors. NMDA receptors (NMDAR) have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDAR play a role in neuronal development and has been implicated in several disorders of the central nervous system including Alzheimer's Disease, epilepsy and ischemic neuronal cell death. Overexpression of the NR2B subunit of the receptor has been associated with increases in learning and memory while aged, memory impaired animals have deficiencies in NR2B expression. Tyr1472 on NR2B is phosphor |
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| Immunogen | n/a |
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| Other Names | Glutamate [NMDA] receptor subunit epsilon 2 precursor, GRIN2B, hNR3, N-methyl D-aspartate receptor subtype 2B, N-methyl-D-aspartate receptor subtype 2B, N-methyl-D-aspartate receptor subunit 3, NMDE2, NME2, NR2B, NR3 |
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| Gene, Accession # | Entrez: 24410, 2904, 494009; Uniprot: Q00960, Q13224, Q5R1P3 |
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| Catalog # | 32-0700 |
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| Order / More Info | NMDAR2B Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 16421318, 22674573, 8859015 |
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