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| Antigenic Specificity | CLCNKA |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1:200-1:500 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CLCNKA Polyclonal Antibody. CLC-KA is a kidney-specific chloride channel that mediates transepithelial chloride transport in the thin ascending limb of the Henle loop in the inner medulla. CLC-KA plays a crucial role in urine concentration. The gene encoding human CLC-KA maps to chromosome 1p36. Mutations in this gene may be associated with nephrogenic diabetes insipidus in those cases where mutations in the vasopressin V2 receptor and the AQP2 water channel are lacking. CLC-KB mediates basolateral chloride ion efflux in the thick ascending limb and in more distal nephron segments. The gene encoding human CLC-KB maps to chromosome 1p36. Mutations in this gene cause type III Barter's syndrome which is characterized by renal salt-wasting and |
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| Immunogen | n/a |
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| Other Names | Chloride channel protein ClC-Ka, Chloride channel Ka, ClC-K1, CLC-KA, CLCKA |
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| Gene, Accession # | Entrez: 1187; Uniprot: P51800 |
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| Catalog # | PA5-63472 |
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| Price | |
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| Order / More Info | CLCNKA Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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