产品详情 |
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Antigenic Specificity | CD148 |
Clone | MEM-CD148/05 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry: 2-5 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD148 Monoclonal Antibody (MEM-CD148/05). CD148 is a highly glycosylated transmembrane protein of up to 250 kDa, containing eight fibronectin type III domains in the extracellular region and one tyrosine phosphatase domain in the cytoplasmic region. Expression is found broadly on fibroblasts, epithelial cells, lymphocytes (B, T and NK cells), and myeloid cells (monocytes and granulocytes). CD148 can dephosphorylate proteins such as LAT and PLC-gamma, and is involved in the downregulation of T cell activation. Conversely, CD148 expression can be upregulated following T cell activation. |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | Entrez: 5795; Uniprot: Q12913 |
Catalog # | MA5-28592 |
Price | |
Order / More Info | CD148 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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