产品详情 |
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Antigenic Specificity | IFIT5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL, Western Blot: 1:500 - 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IFIT5 Polyclonal Antibody. Interferon-induced RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Also recognizes and binds tRNAs. |
Immunogen | n/a |
Other Names | ISG58; RI58 |
Gene, Accession # | Entrez: 24138; Uniprot: Q13325 |
Catalog # | PA5-66464 |
Price | |
Order / More Info | IFIT5 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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