| 产品详情 |
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| Antigenic Specificity | HTRA1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | bovine, canine, human, mouse, nonhuman primate, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:10-1:2000, Immunofluorescence: 1:10-1:2000, Western Blot: 1:250-1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | HTRA1 Polyclonal Antibody. HtrA1, a 51KDa protein, is a member of highly conserved mammalian HtrA serine protease family. It is a human homolog of bacterial HtrA and consists of a secretory signal sequence, an IGFBP-binding domain and a Kazal-type serine-protease inhibitor domain at the N-terminus and a highly conserved trypsin-like serine/protease domain and a PDZ domain at the C-terminus. It plays a major role in the regulation of cell growth. HtrA1 inhibits signaling mediated by TGF-beta family members and regulates many physiological processes. HtrA1 is up-regulated in placenta during pregnancy and plays an important role in implantation and placental physiology. It regulates the availability of IGFs by cleaving IGF-binding proteins. It |
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| Immunogen | n/a |
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| Other Names | ARMD7, HtrA, L56, ORF480, PRSS11, IGFBP5-protease, high-temperature requirement A serine peptidase 1, protease, serine, 11 (IGF binding), serine protease HTRA1 |
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| Gene, Accession # | Entrez: 282326, 477852, 56213, 5654, 65164; Uniprot: F1N152, Q92743, Q9QZK5, Q9R118 |
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| Catalog # | PA5-23395 |
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| Price | |
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| Order / More Info | HTRA1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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