产品详情 |
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Antigenic Specificity | IFI6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IFI6 Polyclonal Antibody. G1P3, also known as Interferon alpha-inducible protein 6 (IFI6) and Interferon-induced protein 6-16, is a 130 amino acid member of the IFI6 family of proteins. Localized to the mitochondria, G1P3 is a multi-pass membrane protein that is induced by IFN-α2β. G1P3 has been shown to play a major role in the apoptosis pathway. Specifically, G1P3 acts as a cell survival protein by inhibiting caspase-3 activity, which antagonizes apoptosis. G1P3 has been implicated in tumorigenesis and is the subject of therapeutic studies, as reducing G1P3-mediated antiapoptotic signals could suggest improved therapies for myeloma or other malignancies. |
Immunogen | n/a |
Other Names | Ifi-6-16; IFI6; IFI6_HUMAN; Interferon alpha-inducible protein 6; Interferon-induced protein 6-16; |
Gene, Accession # | Entrez: 2537; Uniprot: P09912 |
Catalog # | PA5-76860 |
Price | |
Order / More Info | IFI6 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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