产品详情 |
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Antigenic Specificity | Claudin 4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | ELISA: 0.1-1 µg/mL, Immunofluorescence: Assay Dependent, Immunoprecipitation: 1-3 µg/mL, Western Blot: 1-3 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Claudin 4 Polyclonal Antibody (ZMD.306). Claudin-4 belongs to the 20-member family of claudins, transmembrane cellular adhesion proteins localized at epithelial and endothelial tight junctions. Claudins demonstrate distinct, tissue-specific expression patterns, and are essential components of tight junction charge-specific channels that regulate paracellular ion flux. Claudin-4 is a component of tight junction strands and may play a role in internal organ development and function during pre- and postnatal life. The overexpression of Claudin-4 has been shown to decrease paracellular electrical conductance due to a selective decrease in Na+ permeability, with no significant decrease in Cl- permeability. In ovarian carcinoma cells, |
Immunogen | n/a |
Other Names | CLAUDIN4, Claudin-4, CLDN4, CPER, CPE-R, CPETR, CPETR1, WBSCR8 |
Gene, Accession # | Entrez: 12740, 304407; Uniprot: O35054 |
Catalog # | 36-4800 |
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Order / More Info | Claudin 4 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 11375422, 12853285, 17277780, 17447253, 18786529, 19117052, 19553471, 19706291, 19898610, 19955175, 20505164, 21109991, 21191420, 21257729, 22724083, 22886143, 23470164, 23639809, 23690579, 24263106, 24830343, 24909426, 24955347, 24993944, 25053428, 25299782, 25412440, 25789658, 25888574, 25907035, 26319240, 26527742, 27030194, 27130254, 27291930, 27797821 |
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