| 产品详情 |
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| Antigenic Specificity | Claudin 2 |
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| Clone | 12H12 |
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| Host Species | Mouse |
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| Reactive Species | canine, human, mouse, rat |
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| Isotype | IgG2b |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunofluorescence: 1-3 µg/mL, Immunohistochemistry (Paraffin): 1:10-1:100, Immunoprecipitation: Assay Dependent, Western Blot: 1-3 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Claudin 2 Monoclonal Antibody (12H12). Mouse Claudin-2 was discovered in 1998 as a 230 amino acid protein localizing at tight junctions with an approximate molecular weight of 22.9 kDa. Claudin-1 and Claudin-2 are structurally related, and are 38% identical at the amino acid sequence level. Claudin-2 belongs to the claudin family of integral membrane proteins. Claudins are responsible for the formation of tight junction strands, and are connected to the actin cytoskeleton through ZO-1. Claudin-2 functions as a paracellular channel with cation (Na+) selectivity at tight junctions. The expression of Claudin-2 is restricted to the liver and kidney, with small amounts also found in the brain.Tight junctions (TJs) are specialized membrane domain |
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| Immunogen | n/a |
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| Other Names | CLDN2, SP82, CLD2 |
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| Gene, Accession # | Entrez: 12738, 300920, 403649, 9075; Uniprot: O88552, P57739, Q95KM6 |
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| Catalog # | 32-5600 |
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| Price | |
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| Order / More Info | Claudin 2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 12700140, 12909588, 16387471, 16505274, 16723500, 17487939, 18031476, 18097951, 18479414, 18711353, 18838552, 18955738, 19082451, 19084987, 19468668, 19805521, 20124215, 20204275, 21383692, 21717371, 21757541, 22268650, 22315225, 22396724, 22397627, 22645303, 22760423, 22819673, 22946046, 23143602, 23253490, 23357502, 23470164, 23553632, 23592547, 23608536, 24294371, 24614073, 24907557, 24908389, 24909426, 24948117, 25075044, 25084053, 25101232, 25157572, 25222658, 25393310, 25513955, 25781928, 25782989, 25795020, 25820018, 25823815, 25948735, 26063734, 26206859, 27002723, 27120348, 27223826, 27431777, 27492331, 27592562, 27598247, 27600198, 28698546, 28861400 |
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