产品详情 |
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Antigenic Specificity | Caspase 9 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunocytochemistry: 2 µg/mL, Immunofluorescence: 20 µg/mL, Immunoprecipitation: Assay Dependent, Western Blot: 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Caspase 9 Polyclonal Antibody. Caspase 9 (ICE-like apoptotic protease 6, ICE LAP6, apoptotic protease Mch6, apoptotic protease activating factor 3, Apaf3) is a member of the peptidase family C14 that contains a CARD domain. Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspase 9 is active as a heterotetramer, is present in the cytosol and, upon activation, translocates to the mitochondria. Caspase 9 is involved in the caspase activation cascade responsible for apoptosis execution and cleaves/activates Caspase 3 and Caspase 6. Further, Caspase 9 is involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf- |
Immunogen | n/a |
Other Names | RP11-265F14.3, APAF-3, APAF3, CASPASE-9c, ICE-LAP6, MCH6, PPP1R56; ICE-like apoptotic protease 6; apoptotic protease MCH-6; apoptotic protease activating factor 3; caspase-9; protein phosphatase 1, regulatory subunit 56; cas9 |
Gene, Accession # | Entrez: 842; Uniprot: P55211 |
Catalog # | PA5-19904 |
Price | |
Order / More Info | Caspase 9 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 26171069 |
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