产品详情 |
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Antigenic Specificity | Caspase 9 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | bovine, human, mouse, ovine, rat |
Isotype | n/a |
Format | purified |
Size | 500 µL |
Concentration | n/a |
Applications | Hemagglutination Assay: 3-5 µg/1x10^6 cells, Immunohistochemistry (Paraffin): 1:20, Immunoprecipitation: 10 µg/mg protein lysate, Western Blot: 1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Caspase 9 Polyclonal Antibody. Caspase 9 (ICE-like apoptotic protease 6, ICE LAP6, apoptotic protease Mch6, apoptotic protease activating factor 3, Apaf3) is a member of the peptidase family C14 that contains a CARD domain. Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspase 9 is active as a heterotetramer, is present in the cytosol and, upon activation, translocates to the mitochondria. Caspase 9 is involved in the caspase activation cascade responsible for apoptosis execution and cleaves/activates Caspase 3 and Caspase 6. Further, Caspase 9 is involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf- |
Immunogen | n/a |
Other Names | CASP-9, ICE-like apoptotic protease 6,apoptotic protease MCH-6, apoptotic protease activating factor 3, apoptotic protease-activating factor 3, caspase 9, apoptosis-related cysteine protease, caspase-9, cas9 |
Gene, Accession # | Entrez: 100140945, 101110953, 12371, 58918, 842; Uniprot: P55211, Q8C3Q9 |
Catalog # | PA5-16358 |
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Order / More Info | Caspase 9 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 22281060, 22424351, 22974427, 23457494, 23773821, 23815517, 26090867, 26364502 |
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