产品详情 |
Edit |   |
Antigenic Specificity | Caspase 9 |
Clone | LAP6 96-2-22 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | purified |
Size | 200 µL |
Concentration | n/a |
Applications | Immunocytochemistry: 1:50-1:250, Immunofluorescence: 1:50-1:250, Immunohistochemistry (Paraffin): 1:50-1:250, Western Blot: 1:500 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Caspase 9 Monoclonal Antibody (LAP6 96-2-22). Caspase 9 (ICE-like apoptotic protease 6, ICE LAP6, apoptotic protease Mch6, apoptotic protease activating factor 3, Apaf3) is a member of the peptidase family C14 that contains a CARD domain. Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspase 9 is active as a heterotetramer, is present in the cytosol and, upon activation, translocates to the mitochondria. Caspase 9 is involved in the caspase activation cascade responsible for apoptosis execution and cleaves/activates Caspase 3 and Caspase 6. Further, Caspase 9 is involved in the activation cascade of caspases responsible for apoptosis execution. Binding of cas |
Immunogen | n/a |
Other Names | RP11-265F14.3, APAF-3, APAF3, CASPASE-9c, ICE-LAP6, MCH6, cas9 |
Gene, Accession # | Entrez: 842; Uniprot: P55211 |
Catalog # | MA1-16842 |
Price | |
Order / More Info | Caspase 9 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 16730720, 21368565 |
产品资料 |
|
|